TITLE YEAR

 

A microfluidic cell-migration assay for the prediction of progression-free survival and recurrence time of patients with glioblastoma

BS Wong, SR Shah, CL Yankaskas, VK Bajpai, PH Wu, D Chin, ...
Nature Biomedical Engineering, 1-15
 
2020
A Tppp3+ pdgfra+ tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis
T Harvey, S Flamenco, CM Fan
Nature cell biology 21 (12), 1490-1503
 
2019
Muscle stem cell renewal suppressed by GAS1 can be reversed by GDNF in mice
L Li, M Rozo, S Yue, X Zheng, FJ Tan, C Lepper, CM Fan
Nature metabolism 1 (10), 985-995
 
2019
Effects of Aging on the Viscoelastic Properties of Tissues and Cancer Cell Behavior
S Park, J Tao, L Sun, CM Fan, Y Chen
Biophysical Journal 116 (3), 296a
 
2019
An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
S Park, J Tao, L Sun, CM Fan, Y Chen
Molecules 24 (5), 907
 
2019
Origin of tendon stem cells in situ
T Harvey, CM Fan
Frontiers in Biology 13 (4), 263-276
 
2018
A CREB-MPP7-AMOT regulatory axis controls muscle stem cell expansion and self-renewal competence
L Li, CM Fan
Cell reports 21 (5), 1253-1266
 
2017
Interleukins 4 and 13 Induce Exon Skipping of Mutant Dystrophin Pre-mRNA to Restore Dystrophin Production
SH Low, CM Fan
bioRxiv, 207480
 
2017
Quantitative 3D Time Lapse Imaging of Muscle Progenitors in Skeletal Muscle of Live Mice
MT Webster, T Harvey, CM Fan
Bio-protocol 6 (24)
 
2016
Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis
GM Xavier, M Seppala, SN Papageorgiou, CM Fan, MT Cobourne
Oncotarget 7 (48), 79233
 
2016
Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice
M Rozo, L Li, CM Fan
Nature medicine 22 (8), 889-896
 
2016
Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice
L Lukjanenko, MJ Jung, N Hegde, C Perruisseau-Carrier, E Migliavacca, ...
Nature medicine 22 (8), 897-905
 
2016
Intravital imaging reveals ghost fibers as architectural units guiding myogenic progenitors during regeneration
MT Webster, U Manor, J Lippincott-Schwartz, CM Fan
Cell stem cell 18 (2), 243-252
 
2016
Growth arrest specific-1 (GAS1) is a C/EBP target gene that functions in ovulation and corpus luteum formation in mice
YA Ren, Z Liu, LK Mullany, CM Fan, JAS Richards
Biology of reproduction 94 (2), 44, 1-12
 
2016
WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals
M Kann, E Bae, MO Lenz, L Li, BT Trannguyen, VA Schumacher, ...
Development 142 (7), 1254-1266
 
2015
Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway
D Van Mater, L Añó, JM Blum, MT Webster, WQ Huang, N Williams, Y Ma, ...
Cancer research 75 (3), 605-614
 
2015
Gas1 is a receptor for sonic hedgehog to repel enteric axons
S Jin, DC Martinelli, X Zheng, M Tessier-Lavigne, CM Fan
Proceedings of the National Academy of Sciences 112 (1), E73-E80
 
2015
HDAC 4 promotes P ax7‐dependent satellite cell activation and muscle regeneration
MC Choi, S Ryu, R Hao, B Wang, M Kapur, CM Fan, TP Yao
EMBO reports 15 (11), 1175-1183
 
2014
Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function
M Seppala, GM Xavier, CM Fan, MT Cobourne
Biology open 3 (8), 728-740
 
2014
A series of Cre‐ERT2 drivers for manipulation of the skeletal muscle lineage
S Southard, SH Low, L Li, M Rozo, T Harvey, CM Fan, C Lepper
genesis 52 (8), 759-770
 
2014
The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling
RH Khonsari, M Seppala, A Pradel, H Dutel, G Clement, O Lebedev, ...
BMC biology 11 (1), 27
 
2013
Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells
JM Blum, L Añó, Z Li, D Van Mater, BD Bennett, M Sachdeva, I Lagutina, ...
Cell reports 5 (4), 933-940
 
2013
c-MET regulates myoblast motility and myocyte fusion during adult skeletal muscle regeneration
MT Webster, CM Fan
PloS one 8 (11), e81757
 
2013
Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells
S Günther, J Kim, S Kostin, C Lepper, CM Fan, T Braun
Cell stem cell 13 (5), 590-601
 
2013
Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion
JEN Minchin, VC Williams, Y Hinits, SH Low, P Tandon, CM Fan, ...
Development 140 (14), 2972-2984
 
2013
Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis
TP Lopez, CM Fan
Proceedings of the National Academy of Sciences 110 (22), E2019-E2027
 
2013
Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling
S Biau, S Jin, CM Fan
Biology open 2 (2), 144-155
 
2013
Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway
SJ Lee, TV Huynh, YS Lee, SM Sebald, SA Wilcox-Adelman, N Iwamori, ...
Proceedings of the National Academy of Sciences 109 (35), E2353-E2360
 
2012
A transgenic Tbx6;CreERT2 line for inducible gene manipulation in the presomitic mesoderm
T Peter Lopez, CM Fan
genesis 50 (6), 490-495
 
2012
Making skeletal muscle from progenitor and stem cells: development versus regeneration
CM Fan, L Li, ME Rozo, C Lepper
Wiley Interdisciplinary Reviews: Developmental Biology 1 (3), 315-327
 
2012
Missense substitutions in the GAS1 protein present in holoprosencephaly patients reduce the affinity for its ligand, SHH
DE Pineda-Alvarez, E Roessler, P Hu, K Srivastava, BD Solomon, ...
Human genetics 131 (2), 301-310
 
2012
Generating tamoxifen-inducible Cre alleles to investigate myogenesis in mice
C Lepper, CM Fan
Myogenesis, 297-308
 
2012
Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells
Y Kim, AA Sharov, K McDole, M Cheng, H Hao, CM Fan, N Gaiano, ...
Science 334 (6063), 1706-1710
 
2011
An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration
C Lepper, TA Partridge, CM Fan
Development 138 (17), 3639-3646
 
2011
Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons
N Osterberg, M Wiehle, O Oehlke, S Heidrich, C Xu, CM Fan, K Krieglstein, ...
PloS one 6 (4), e19239
 
2011
B-type lamins regulates neither their bound genes nor embryonic stem cells but are essential for organogenesis
Y Kim, A Sharov, K Mcdole, M Cheng, H Hao, CM Fan, N Gaiano, M Ko, ...
MOLECULAR BIOLOGY OF THE CELL 22
 
2011
Inducible lineage tracing of Pax7‐descendant cells reveals embryonic origin of adult satellite cells
C Lepper, CM Fan
genesis 48 (7), 424-436
 
2010
A role for borg5 during trophectoderm differentiation
QP Vong, Z Liu, JG Yoo, R Chen, W Xie, AA Sharov, CM Fan, C Liu, ...
Stem cells 28 (6), 1030-1038
 
2010
Counterfeiting the family jewels
A Spradling, CM Fan
Cell stem cell 6 (5), 405-406
 
2010
A sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1
DC Martinelli, CM Fan
Journal of Biological Chemistry 284 (29), 19169-19172
 
2009
Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements
C Lepper, SJ Conway, CM Fan
Nature 460 (7255), 627-631
 
2009
Primary cilia regulate Shh activity in the control of molar tooth number
A Ohazama, CJ Haycraft, M Seppala, J Blackburn, S Ghafoor, ...
Development 136 (6), 897-903
 
2009
V3 spinal neurons establish a robust and balanced locomotor rhythm during walking
Y Zhang, S Narayan, E Geiman, GM Lanuza, T Velasquez, B Shanks, ...
Neuron 60 (1), 84-96
 
2008
Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei
C Xu, CM Fan
Gene Expression Patterns 8 (7-8), 502-507
 
2008
Separate Necdin domains bind ARNT2 and HIF1α and repress transcription
ER Friedman, CM Fan
Biochemical and biophysical research communications 363 (1), 113-118
 
2007
The role of Gas1 in embryonic development and its implications for human disease
DC Martinelli, CM Fan
Cell Cycle 6 (21), 2650-2655
 
2007
Genetic interactions between Gas1 and Shh during early craniofacial development
M Seppala, CM Fan, M Depew, P Sharpe, M Cobourne
Genetical Research 89 (3)
 
2007
Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog
M Seppala, MJ Depew, DC Martinelli, CM Fan, PT Sharpe, MT Cobourne
The Journal of clinical investigation 117 (6), 1575-1584
 
2007
Gas1 extends the range of Hedgehog action by facilitating its signaling
DC Martinelli, CM Fan
Genes & development 21 (10), 1231-1243
 
2007
Allocation of Paraventricular and Supraoptic Neurons Requires Sim1 Function: A Role for a Sim1 Downstream Gene PlexinC1
C Xu, CM Fan
Molecular Endocrinology 21 (5), 1234-1245
 
2007
Targeting gene expression in the mouse somite: Adenovirus‐mediated gene delivery and whole embryo culture
AE Chen, CM Fan
genesis 42 (2), 71-76
 
2005
Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins
AE Chen, DD Ginty, CM Fan
Nature 433 (7023), 317-322
 
2005
WNT regulation of myogenesis requires PKA and CREB.
A Chen, D Ginty, CM Fan
DEVELOPMENTAL BIOLOGY 271 (2), 552-552
 
2004
Sim2 Contributes to Neuroendocrine Hormone Gene Expression in the Anterior Hypothalamus
E Goshu, H Jin, J Lovejoy, JF Marion, JL Michaud, CM Fan
Molecular Endocrinology 18 (5), 1251-1262
 
2004
Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction
L Buttitta, R Mo, CC Hui, CM Fan
Development 130 (25), 6233-6243
 
2003
Identification of the downstream targets of SIM1 and ARNT2, a pair of transcription factors essential for neuroendocrine cell differentiation
C Liu, E Goshu, A Wells, CM Fan
Journal of Biological Chemistry 278 (45), 44857-44867
 
2003
GLI2 and GLI3 are required for SHH depedent sclerotome induction.
L Buttitta, CC Hui, CM Fan
DEVELOPMENTAL BIOLOGY 259 (2), 569-569
 
2003
Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm
L Buttitta, TS Tanaka, AE Chen, MSH Ko, CM Fan
Developmental biology 258 (1), 91-104
 
2003
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY-Identification of the Downstream Targets of SIM1 and ARNT2, a Pair of Transcription Factors Essential for Neuroendocrine Cell …
C Liu, E Goshu, A Wells, CM Fan
Journal of Biological Chemistry 278 (45), 44857-44867
 
2003
Hormones, Obesity, Learning, and Breathing — the Many Functions of Mammalian Single-Minded Genes
CM Fan
PAS Proteins: Regulators and Sensors of Development and Physiology, 205-230
 
2003
Growth arrest specific gene 1: a fuel for driving growth in the cerebellum
G Marques, CM Fan
The Cerebellum 1 (4), 259-263
 
2002
Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb
Y Liu, C Liu, Y Yamada, CM Fan
Development 129 (22), 5289-5300
 
2002
Nuclear factors associated with transcriptional regulation
D Baltimore, R Sen, PA Sharp, H Singh, L Staudt, JH LeBowitz, ...
US Patent 6,410,516
 
2002
Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants
E Goshu, H Jin, R Fasnacht, M Sepenski, JL Michaud, CM Fan
Molecular and cellular biology 22 (12), 4147-4157
 
2002
Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite
CS Lee, L Buttitta, CM Fan
Proceedings of the National Academy of Sciences 98 (20), 11347-11352
 
2001
Growth Arrest Specific Gene 1 Is a Positive Growth Regulator for the Cerebellum
Y Liu, NR May, CM Fan
Developmental biology 236 (1), 30-45
 
2001
Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant
CS Lee, NR May, CM Fan
Developmental biology 236 (1), 17-29
 
2001
Gene expression during somitogenesis.
LA Buttitta, TS Tanaka, MS Ko, CM Fan
DEVELOPMENTAL BIOLOGY 235 (1), 268-268
 
2001
Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus
JL Michaud, F Boucher, A Melnyk, F Gauthier, E Goshu, E Lévy, ...
Human molecular genetics 10 (14), 1465-1473
 
2001
Embryonic expression patterns of the mouse and chick Gas1 genes
CS Lee, CM Fan
Mechanisms of development 101 (1-2), 293-297
 
2001
Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS
DJ Epstein, L Martinu, JL Michaud, KM Losos, C Fan, AL Joyner
Development 127 (21), 4701-4709
 
2000
ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus
JL Michaud, C DeRossi, NR May, BC Holdener, CM Fan
Mechanisms of development 90 (2), 253-261
 
2000
SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm
CS Lee, LA Buttitta, NR May, A Kispert, CM Fan
Development 127 (1), 109-118
 
2000
Remembrance of things PAS: regulation of development by bHLH–PAS proteins
ST Crews, CM Fan
Current opinion in genetics & development 9 (5), 580-587
 
1999
Development of neuroendocrine lineages requires the bHLH–PAS transcription factor SIM1
JL Michaud, T Rosenquist, NR May, CM Fan
Genes & development 12 (20), 3264-3275
 
1998
Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
JA McMahon, S Takada, LB Zimmerman, CM Fan, RM Harland, ...
Genes & development 12 (10), 1438-1452
 
1998
A role for WNT proteins in induction of dermomyotome
CM Fan, CS Lee, M Tessier-Lavigne
Developmental biology 191 (1), 160-165
 
1997
Single-minded—two genes, three chromosomes
J Michaud, CM Fan
Genome research 7 (6), 569-571
 
1997
Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein
MR Probst, CM Fan, M Tessier-Lavigne, O Hankinson
Journal of Biological Chemistry 272 (7), 4451-4457
 
1997
Early deletion of neuromeres in Wnt‐1‐/‐ mutant mice: Evaluation by morphological and molecular markers
GS Mastick, CM Fan, M Tessier‐Lavigne, GN Serbedzija, AP McMahon, ...
Journal of Comparative Neurology 374 (2), 246-258
 
1996
Lateral and axial signals involved in avian somite patterning: a role for BMP4
O Pourquié, CM Fan, M Coltey, E Hirsinger, Y Watanabe, C Bréant, ...
Cell 84 (3), 461-471
 
1996
Expression Patterns of Two Murine Homologs ofDrosophila Single-MindedSuggest Possible Roles in Embryonic Patterning and in the Pathogenesis of Down Syndrome
CM Fan, E Kuwana, A Bulfone, CF Fletcher, NG Copeland, NA Jenkins, ...
Molecular and Cellular Neuroscience 7 (1), 1-16
 
1996
Physical mapping of the holoprosencephaly critical region in 21q22. 3, exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of …
M Muenke, LJ Bone, HF Mitchell, I Hart, K Walton, K Hall-Johnson, ...
American journal of human genetics 57 (5), 1074
 
1995
Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway
CM Fan, JA Porter, C Chiang, DT Chang, PA Beachy, M Tessier-Lavigne
Cell 81 (3), 457-465
 
1995
Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog
CM Fan, M Tessier-Lavigne
Cell 79 (7), 1175-1186
 
1994
DORSOVENTRAL PATTERNING OF MAMMALIAN SOMITES-A ROLE FOR EPIDERMIS IN PATTERNING THE DERMOMYOTOME
CM FAN, M TESSIERLAVIGNE
JOURNAL OF CELLULAR BIOCHEMISTRY, 476-476
 
1994
Positive and Negative Control of Human Interferon- Gene Expression
T Maniatis, LA Whittemore, W Du, CM Fan
COLD SPRING HARBOR MONOGRAPH SERIES 22, 1193-1193
 
1993
Generation of p50 subunit of NF-k B by processing of p105 through an ATP-dependent pathway
CM Fan, T Maniatis
Nature 354 (6352), 395-398
 
1991
lymphoma c-myc alleles
DP Lane, S Benchimol, P Pondaven, L Meijer, D Beach, RA Firtel, ...
GENES & DEVELOPMENT
 
1990
A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.
CM Fan, T Maniatis
Genes & development 4 (1), 29-42
 
1990
The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction
MJ Lenardo, CM Fan, T Maniatis, D Baltimore
Cell 57 (2), 287-294
 
1989
Two different virus‐inducible elements are required for human beta‐interferon gene regulation.
CM Fan, T Maniatis
The EMBO Journal 8 (1), 101-110
 
1989