Baltimore, MD--Cells in the body wear down over time and die. In many organs, like the small intestine, adult stem cells play a vital role in maintaining function by replacing old cells with new ones. Learning about the nature of tissue stem cells can help scientists understand exactly how our organs are built, and why some organs generate cancer frequently, but others only rarely.
Read More...
Baltimore, MD—Mammalian females ovulate periodically over their reproductive lifetimes, placing significant demands on their ovaries for egg production. Whether mammals generate new eggs in adulthood using stem cells has been a source of scientific controversy. If true, these “germ-line stem cells” might allow novel treatments for infertility and other diseases.
Read More...
Baltimore, MD— Eggs take a long time to produce in the ovary, and thus are one of a body’s precious resources. It has been theorized that the body has mechanisms to help the ovary ensure that ovulated eggs enter the reproductive tract at the right time in order to maximize the chance of successful fertilization.  
Read More...
Baltimore, MD--Recent research shows that natural experiences in childhood boost creativity, stimulate learning, and improve behavior and health.
Read More...
Baltimore, MD— The ability of embryonic stem cells to differentiate into different types of cells with different functions is regulated and maintained by a complex series of chemical interactions, which are not well understood. Learning more about this process could prove useful for stem cell-based therapies down the road.
Read More...
Washington, D.C.—The Carnegie Institution for Science and the University of Massachusetts Medical School (UMMS) have been granted United States Patent 8,283,329, entitled, “Genetic inhibition of double-stranded RNA.” The patent, issued on October 9, 2012, is broadly directed to the use of RNA interference (RNAi) to inhibit expression of a target gene in animal cells, including mammalian cells.  
Read More...
Baltimore, MD —You may think you have dinner all to yourself, but you’re actually sharing it with a vast community of microbes waiting within your digestive tract. A new study from a team including Carnegie’s Steve Farber and Juliana Carten reveals that some gut microbes increase the absorption of dietary fats, allowing the host organism to extract more calories from the same amount of food.
Read More...
Baltimore, MD—Director Emeritus Donald Brown, of Carnegie’s Department of Embryology, receives the prestigious 2012 Lasker-Koshland Special Achievement Award in Medical Science “For exceptional leadership and citizenship in biomedical science–exemplified by fundamental discoveries concerning the nature of genes; and by selfless commitment to young scientists.” Brown is honored along with Tom Maniatis of Columbia University.  
Read More...
Baltimore, MD — The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known about how myostatin affects muscle growth, there has been disagreement about what types of muscle cells it acts upon.
Read More...
Baltimore, MD — In mammals, most lipids (such as fatty acids and cholesterol) are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. New research from Carnegie’s Steven Farber, James Walters and Jennifer Anderson reveals a technique that allows scientists to watch lipid metabolism in live zebrafish.
Read More...
Baltimore, MD — Insect glands are responsible for producing a host of secretions that allow bees to sting and ants to lay down trails to and from their nests. New research from Carnegie scientists focuses on secretions from glands in the reproductive tract that help sperm survive and guide the sperm on the trip to fertilize an egg.
Read More...
Baltimore, MD—Carnegie’s educational outreach program, BioEYES, will be the recipient of the 2012 Viktor Hamburger Outstanding Educator Prize from the Society for Developmental Biology. BioEYES founders Steve Farber and Jamie Shuda (University of Pennsylvania), will accept the award at the upcoming annual meeting of the society in Montreal in July.
Read More...
Baltimore, MD — Scientists have long held theories about the importance of proteins called B-type lamins in the process of embryonic stem cells replicating and differentiating into different varieties of cells.
Read More...
Baltimore, MD—Carnegie’s educational outreach program, BioEYES, has joined forces with General Motors (GM), and Earth Force to take Walter P. Carter Elementary/Middle School students on a knee-deep watershed lesson on December 1, 2011.
Read More...
Baltimore, MD—Staff associate Christoph Lepper, at Carnegie’s Department of Embryology, is one of 10 recipients of the NIH Director’s Early Independence Awards. This is the first year of the awards. Lepper will receive a prize of $250,000 per year for five years to carry out his creative research program as an independent investigator.
Read More...